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Red blood cell distribution width is not related with inflammatory parameters in morbidly obese patients.

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In this context, toxicity is relevant in determining if health outcomes are improved.

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Das im Emirat ansässige Pharmaunternehmen Julphar (Gulf Pharmaceuticals Industries) stellt eine EPO-α-Variante unter dem Handelsnamen Epotin her.

Darbepoetin (Aranesp): 2002 FDA clinical (medical officer) review (redacted).

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In addition, filgrastim is a very well-characterizable, nonglycosylated molecule, and close similarity of the molecular structure together with the absence of impurities or excipients of concern already provide substantial reassurance that the resulting product will not be associated with undue immunogenicity.

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If an immune response to the reference is rare, two separate studies may be sufficient to evaluate immunogenicity: 1) premarket study to detect major differences in immune responses between biosimilar and reference; 2) postmarket study to detect subtle differences in immunogenicity.

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Recent evidence suggests that the use of either marker may contribute to both the diagnosis and prognostic outcome in patients with acute coronary syndrome (ACS).

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